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Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model.
Ahmad S, Wrennall JA, Goriounova AS, Sekhri M, Iskarpatyoti JA, Ghosh A, Abdelwahab SH, Voeller A, Rai M, Mahida RY, Krajewski K, Ignar DM, Greenbaum A, Moran TP, Tilley SL, Thickett DR, Sassano MF, Tarran R. Ahmad S, et al. Among authors: iskarpatyoti ja. Am J Respir Crit Care Med. 2024 Mar 15;209(6):703-715. doi: 10.1164/rccm.202308-1393OC. Am J Respir Crit Care Med. 2024. PMID: 37972349
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates.
Goubau D, Schlee M, Deddouche S, Pruijssers AJ, Zillinger T, Goldeck M, Schuberth C, Van der Veen AG, Fujimura T, Rehwinkel J, Iskarpatyoti JA, Barchet W, Ludwig J, Dermody TS, Hartmann G, Reis e Sousa C. Goubau D, et al. Among authors: iskarpatyoti ja. Nature. 2014 Oct 16;514(7522):372-375. doi: 10.1038/nature13590. Epub 2014 Aug 10. Nature. 2014. PMID: 25119032 Free PMC article.
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.
Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker HC, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B. Bouziat R, et al. Among authors: iskarpatyoti ja. Science. 2017 Apr 7;356(6333):44-50. doi: 10.1126/science.aah5298. Science. 2017. PMID: 28386004 Free PMC article.
Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18.
Zhang B, Chassaing B, Shi Z, Uchiyama R, Zhang Z, Denning TL, Crawford SE, Pruijssers AJ, Iskarpatyoti JA, Estes MK, Dermody TS, Ouyang W, Williams IR, Vijay-Kumar M, Gewirtz AT. Zhang B, et al. Among authors: iskarpatyoti ja. Science. 2014 Nov 14;346(6211):861-5. doi: 10.1126/science.1256999. Science. 2014. PMID: 25395539 Free PMC article.